Oxytocin protects against sepsis-induced multiple organ damage: Role of neutrophils


Iseri S., Sener G. , Saglam B., Gedik N., Ercan F. , Yegen B.

JOURNAL OF SURGICAL RESEARCH, cilt.126, sa.1, ss.73-81, 2005 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 126 Konu: 1
  • Basım Tarihi: 2005
  • Doi Numarası: 10.1016/j.jss.2005.01.021
  • Dergi Adı: JOURNAL OF SURGICAL RESEARCH
  • Sayfa Sayıları: ss.73-81

Özet

Background. Sepsis, commonly associated with enhanced generation of reactive oxygen metabolites, leads to multiple organ dysfunctions. The neurohypophyseal hormone oxytocin (OT), released during social contact, was recently shown to modulate the immune and inflammatory processes. We investigated the protective role of OT against sepsis-induced pelvic inflammation.