Caffeic acid phenethyl ester (CAPE) prevents methotrexate-induced hepatorenal oxidative injury in rats

Cakir T., Ozkan E., Dulundu E., Topaloglu U., Sehirli A. O., ERCAN F., ...Daha Fazla

JOURNAL OF PHARMACY AND PHARMACOLOGY, cilt.63, sa.12, ss.1566-1571, 2011 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 63 Sayı: 12
  • Basım Tarihi: 2011
  • Doi Numarası: 10.1111/j.2042-7158.2011.01359.x
  • Dergi Adı: JOURNAL OF PHARMACY AND PHARMACOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1566-1571
  • Anahtar Kelimeler: caffeic acid phenethyl ester, kidney, liver, methotrexate, oxidative damage, INDUCED NEPHROTOXICITY, LIPID-PEROXIDATION, STRESS, ANTIOXIDANT, KIDNEY, PROPOLIS, CELLS, LIVER, MYELOPEROXIDASE, PHARMACOLOGY
  • Marmara Üniversitesi Adresli: Evet

Özet

Objectives This study aimed to investigate the antioxidant and anti-inflammatory effects of caffeic acid phenethyl ester (CAPE) on the methotrexate (MTX)-induced hepatorenal oxidative damage in rats.