Biologic tumor behavior in pilocytic astrocytomas

Belirgen M., Berrak S. G., ÖZDAĞ H., Bozkurt S. U., Eksioglu-Demiralp E., Ozek M. M.

CHILDS NERVOUS SYSTEM, vol.28, no.3, pp.375-389, 2012 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 28 Issue: 3
  • Publication Date: 2012
  • Doi Number: 10.1007/s00381-011-1676-6
  • Journal Name: CHILDS NERVOUS SYSTEM
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.375-389
  • Keywords: Pilocytic astrocytomas, Immunohistochemistry, Tumor suppressor proteins, Flow cytometry, Microarray, CGH, Copy number aberration, COMPARATIVE GENOMIC HYBRIDIZATION, ENDOTHELIAL GROWTH-FACTOR, RETINOBLASTOMA PROTEIN EXPRESSION, BENIGN CEREBELLAR ASTROCYTOMA, MIB-1 LABELING INDEX, BRAIN-TUMORS, PTEN GENE, GLIOBLASTOMA-MULTIFORME, CEREBRAL HEMISPHERES, DIFFUSE ASTROCYTOMAS
  • Marmara University Affiliated: Yes

Abstract

The aim is to describe the behavior of pilocytic astrocytoma (PAs) and its effects on patient prognosis by using flow cytometric, immunohistochemical and cytogenetic methods. We also aim to find out whether there is any difference between differently localized tumors by the above mentioned analyses.