Myelodysplastic syndrome associated with monosomy 7 in a child with Bloom syndrome


Aktas D., Koc A. , Boduroglu K., Hicsonmez G., Tuncbilek E.

CANCER GENETICS AND CYTOGENETICS, vol.116, no.1, pp.44-46, 2000 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 116 Issue: 1
  • Publication Date: 2000
  • Doi Number: 10.1016/s0165-4608(99)00099-0
  • Title of Journal : CANCER GENETICS AND CYTOGENETICS
  • Page Numbers: pp.44-46

Abstract

Bloom syndrome is a genomic instability syndrome associated with predisposition to development of various types of malignancy. In this report, rye described a 7-year-old boy with Bloom syndrome (BS) and myelodysplastic syndrome (MDS) associated with monosomy 7 and loss of the Y chromosome. To our knowledge, this was the first case with BS showing monosomy 7 and MDS during the early childhood period. (C) 1999 Elsevier Science Inc., 1999. All rights reserved.