Myelodysplastic syndrome associated with monosomy 7 in a child with Bloom syndrome

Aktas D., Koc A., Boduroglu K., Hicsonmez G., Tuncbilek E.

CANCER GENETICS AND CYTOGENETICS, cilt.116, sa.1, ss.44-46, 2000 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 116 Sayı: 1
  • Basım Tarihi: 2000
  • Doi Numarası: 10.1016/s0165-4608(99)00099-0
  • Dergi Adı: CANCER GENETICS AND CYTOGENETICS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.44-46
  • Marmara Üniversitesi Adresli: Hayır

Özet

Bloom syndrome is a genomic instability syndrome associated with predisposition to development of various types of malignancy. In this report, rye described a 7-year-old boy with Bloom syndrome (BS) and myelodysplastic syndrome (MDS) associated with monosomy 7 and loss of the Y chromosome. To our knowledge, this was the first case with BS showing monosomy 7 and MDS during the early childhood period. (C) 1999 Elsevier Science Inc., 1999. All rights reserved.