Toll-like receptor expression in monocytes in patients with chronic kidney disease and haemodialysis: relation with inflammation

KOÇ M., Toprak A., Arikan H., ODABAŞI Z., Elbir Y., Tulunay A., ...Daha Fazla

NEPHROLOGY DIALYSIS TRANSPLANTATION, cilt.26, sa.3, ss.955-963, 2011 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 26 Sayı: 3
  • Basım Tarihi: 2011
  • Doi Numarası: 10.1093/ndt/gfq500
  • Dergi Adı: NEPHROLOGY DIALYSIS TRANSPLANTATION
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.955-963
  • Anahtar Kelimeler: chronic kidney disease, haemodialysis, inflammation, Toll-like receptor, PERIPHERAL-BLOOD LEUKOCYTES, TUMOR-NECROSIS-FACTOR, STAGE RENAL-DISEASE, INNATE IMMUNITY, TOLL-LIKE-RECEPTOR-4, INDUCTION, CELLS, INTERLEUKIN-6, ACTIVATION, CYTOKINES
  • Marmara Üniversitesi Adresli: Evet

Özet

Background. Inflammation is one of the main contributors to atherosclerosis in haemodialysis (HD) patients. Activation of Toll-like receptors (TLRs) leads to inflammatory response. In this study, we aimed to evaluate the expression of TLRs on monocytes and relate their expression with inflammation in chronic kidney disease (CKD) and HD patients.