Binding of Procaine Hydrochloride to Hydrocarbon and Fluorocarbon Surfactants: The Role of Hydrophobicity

Göktürk S., Bektas S.

JOURNAL OF PHARMACEUTICAL RESEARCH INTERNATIONAL, cilt.22, 2018 (ESCI) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 22
  • Basım Tarihi: 2018
  • Doi Numarası: 10.9734/jpri/2018/41732
  • Dergi Adı: JOURNAL OF PHARMACEUTICAL RESEARCH INTERNATIONAL
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI)
  • Anahtar Kelimeler: Procaine hydrochloride, zonyl FSN-100, surface active drugs, surfactants, micelle, interaction, binding constant, DRUG AMITRIPTYLINE HYDROCHLORIDE, CATIONIC SURFACTANT, BETA-CYCLODEXTRIN, AMPHIPHILIC DRUG, CETYLTRIMETHYLAMMONIUM BROMIDE, PROMETHAZINE HYDROCHLORIDE, MICELLAR SOLUBILIZATION, MIXED MICELLIZATION, ANIONIC SURFACTANT, SOLUTION BEHAVIOR
  • Marmara Üniversitesi Adresli: Evet

Özet

Aims: The interaction of procaine hydrochloride (PC HCl) with sodium dodecyl sulfate (anionic hydrocarbon surfactant; SDS), Tween 20 (nonionic hydrocarbon surfactant), cetyltrimethyl ammonium bromide (cationic hydrocarbon surfactant; CTAB), lauryl sulphate betaine (amphoteric hydrocarbon surfactant; LSB) and Zonyl-FSN100 (non-ionic fluorocarbon surfactant; Zonyl FSN) has been aimed to study by UV-vis spectrophotometry.