Novel M tuberculosis Antigen-Specific T-Cells Are Early Markers of Infection and Disease Progression

Dosanjh D. P. S., Bakir M., Millington K. A., Soysal A., Aslan Y., Efee S., ...More

PLOS ONE, vol.6, no.12, 2011 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 6 Issue: 12
  • Publication Date: 2011
  • Doi Number: 10.1371/journal.pone.0028754
  • Journal Name: PLOS ONE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Marmara University Affiliated: Yes

Abstract

Background: Mycobacterium tuberculosis Region-of-Difference-1 gene products present opportunities for specific diagnosis of M. tuberculosis infection, yet immune responses to only two gene-products, Early Secretory Antigenic Target-6 (ESAT-6) and Culture Filtrate Protein-10 (CFP-10), have been comprehensively investigated.