Can Atopic Diseases be Differentiated from Hyper IgE Syndrome by Serum IgE and Blood Eosinophil Levels?

Kiykim A., Yuce E. G. , Baris E., Nain E., KELEŞ S., Akturk H., ...Daha Fazla

ASTIM ALLERJI IMMUNOLOJI, cilt.15, sa.2, ss.73-81, 2017 (ESCI İndekslerine Giren Dergi) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 15 Konu: 2
  • Basım Tarihi: 2017
  • Doi Numarası: 10.21911/aai.13
  • Sayfa Sayıları: ss.73-81


Objective: High serum IgE and eosinophil counts are laboratory features of severe atopic dermatitis (AD), persistent food allergies and severe allergic asthma as well as some primary immune deficiencies (PID), especially hyperIgE syndrome (HIES). Our objective was to define cut-off values to discriminate atopic diseases and HIES by comparing serum IgE, eosinophil levels, allergen sensitizations among patients with AD, IgE-mediated food allergy, allergic asthma and/or rhinitis, chronic granulomatous disease and HIES.