The effect of losartan and captopril on glomerular basement membrane anionic charge in a diabetic rat model

Yavuz D., Ersoz O., Kucukkaya B., Budak Y., Ahiskali R., Ekicioglu G., ...More

JOURNAL OF HYPERTENSION, vol.17, no.8, pp.1217-1223, 1999 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 17 Issue: 8
  • Publication Date: 1999
  • Doi Number: 10.1097/00004872-199917080-00023
  • Journal Name: JOURNAL OF HYPERTENSION
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1217-1223
  • Marmara University Affiliated: Yes

Abstract

Objective Although angiotensin-converting enzyme inhibitors are known to reduce albuminuria by preserving glomerular basement membrane anionic content, the effects of angiotensin II receptor blockage are currently not known. The aim of this study was to evaluate the effects of captopril and losartan on glomerular basement membrane anionic charges in a diabetic rat model.