Ertapenem versus Standard Triple Antibiotic Therapy for the Treatment of Perforated Appendicitis in Pediatric Patients: A Prospective Randomized Trial


Dalgic N., Karadag C. A., Bayraktar B., SANCAR M., Kara O., Pelit S., ...Daha Fazla

EUROPEAN JOURNAL OF PEDIATRIC SURGERY, cilt.24, sa.5, ss.410-418, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 24 Sayı: 5
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1055/s-0033-1352524
  • Dergi Adı: EUROPEAN JOURNAL OF PEDIATRIC SURGERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.410-418
  • Anahtar Kelimeler: perforated appendicitis, children, ertapenem, bowel flora, VANCOMYCIN-RESISTANT ENTEROCOCCI, SPECTRUM BETA-LACTAMASE, GRAM-NEGATIVE BACILLI, IN-VITRO ACTIVITIES, INTRAABDOMINAL INFECTIONS, KLEBSIELLA-PNEUMONIAE, COMPLICATED APPENDICITIS, PSEUDOMONAS-AERUGINOSA, SUSCEPTIBLE ORGANISMS, INTESTINAL MICROFLORA
  • Marmara Üniversitesi Adresli: Evet

Özet

Background The primary objective of this study was to compare triple therapy with ertapenem treatments in pediatric patients with perforated appendicitis, especially in terms of postoperative infectious complications. The secondary objective of this study was to assess the relative impact of therapy with ertapenem and triple antibiotic regimen on the emergence of resistant bacteria in bowel flora in the patients.