Flip-flop phenomenon in systemic sclerosis on fluorodeoxyglucose positron emission tomography/computed tomography


Oksuzoglu K., Ozen G., İNANIR S. , DİRESKENELİ R. H.

INDIAN JOURNAL OF NUCLEAR MEDICINE, vol.30, no.4, pp.350-351, 2015 (Journal Indexed in ESCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 30 Issue: 4
  • Publication Date: 2015
  • Doi Number: 10.4103/0972-3919.164018
  • Title of Journal : INDIAN JOURNAL OF NUCLEAR MEDICINE
  • Page Numbers: pp.350-351
  • Keywords: Fluorine-18-fluorodeoxyglucose, positron emission tomography/computed tomography, systemic sclerosis

Abstract

Systemic sclerosis (SSc) is a rare autoimmune disease, which may affect multiple organ systems. Fluorine-18-fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) can demonstrate the degree and anatomical extent of involvement in the entire body and coexisting malignancies in connective tissue diseases. We present a case of SSc with an increased 18F-FDG uptake in the cutaneous and subcutaneous tissues even higher than the neighboring skeletal muscles ("flip-flop phenomenon," that is, an increased 18F-FDG uptake in the skin but a decreased 18F-FDG uptake in the skeletal muscles).