Langerhans Hucreli Histiyositoz Tanili Hastada Soliter Kemik Lezyonunun Takibinde Kemik Sintigrafi ve SPECT/BT'nin Rolu

KESİM S., TUROĞLU H. T., İNANIR S., ÖZGÜVEN S., ERDİL T. Y.

MOLECULAR IMAGING AND RADIONUCLIDE THERAPY, vol.30, no.3, pp.187-189, 2021 (ESCI) identifier identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 30 Issue: 3
  • Publication Date: 2021
  • Doi Number: 10.4274/mirt.galenos.2020.20981
  • Journal Name: MOLECULAR IMAGING AND RADIONUCLIDE THERAPY
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.187-189
  • Keywords: Langerhans' cell histiocytosis, technetium-99m-methylene diphosphonate bone scintigraphy, bone SPECT/CT, EMISSION TOMOGRAPHY/COMPUTED TOMOGRAPHY, CELL HISTIOCYTOSIS, BONE-SCINTIGRAPHY, LESIONS
  • Marmara University Affiliated: Yes

Abstract

Langerhans' cell histiocytosis (LCH) is a rare disease observed in childhood characterized by the proliferation of Langerhans' cells resulting in focal or systemic manifestations (including the bones). Here, we present a pediatric case with a localized biopsy-proven LCH, who underwent progression from solitary to multifocal form detected on bone scintigraphy and single photon emission computerized tomography/computed tomography (SPECT/CT) performed within four months. Emphasizing on localized bone pain (predictive of osseous LCH) and local tenderness and swelling usually guides the nuclear physician to perform additional SPECT/CT with presumably an improvement of the diagnostic accuracy as demonstrated in our case.