Mycobacterium vaccae immunization to OVA sensitized pregnant BALB/c mice suppressed placental and postnatal IL-5 and inducing IFN-gamma secretion


AKKOÇ T. , Eifan A. O. , Ozdemir C., Yazi D., Yesil O., Bahceciler N. N. , ...Daha Fazla

IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY, cilt.30, sa.1, ss.1-11, 2008 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 30 Konu: 1
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1080/08923970701812159
  • Dergi Adı: IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY
  • Sayfa Sayıları: ss.1-11

Özet

Although the development of atopy in the newborn is determined by a multitude of factors, an intense Th1 stimulus early in life could be protective by facilitating a switch away from Th2. Aimed to determine the effect of single Mycobacterium vaccae (M. vaccae) immunization to OVA-sensitized pregnant mice on IL-5 and IFN-gamma secretion from placental lymphocytes and splenocytes of offspring.