Impact of the COVID-19 pandemic on the real-world diagnostic infrastructure for tuberculosis—An ESGMYC collaborative study

Paulowski, Laura; Filip, Roxana; Makek, Mateja; Guglielmetti, Lorenzo; Goletti, Delia; van Ingen, Jakko; Kranzer, Katharina; Maurer, Florian; Alcaide, Fernando; Munoz, Fabiola; Cannas, Angela; Chew, Ka; de Steenwinkel, Jurriaan; Egli, Adrian; Esteban, Jaime; Friesen, Inna; Barišić, Ivana; Gonzalez-Galan, Veronica; Gonzalez-Martin, Julian; Althawadi, Sahar; Kalita, Deepjyoti; Karahasan, AYŞEGÜL; Khursheed, Nazia; Konstantynovska, Olha; Kuhns, Martin; Laurenson, Ian; Lina, Gerard; Madeira, Carla; Mareković, Ivana; Mathys, Vanessa; Nisii, Carla; Mazzarelli, Antonio; Opota, Onya; Papaventsis, Dimitrios; Papineni, Padmasayee; Polsfuss, Silke; Porte, Lorena; Sander, Peter; Schön, Thomas; Schulthess, Bettina; Sedlacek, Ludwig; Singh, Sarman; Smith, Michael; Boneva, Biljana; Tahseen, Sabira; Tiberi, Simon; Fernandez, Maria; van Weerdenburg, Ingrid; Vinuelas, Jesus; Žmak, Ljiljana; Žolnir-Dovč, Manca

doi:10.1371/journal.pone.0291404

Impact of the COVID-19 pandemic on the real-world diagnostic infrastructure for tuberculosis—An ESGMYC collaborative study

Atıf İçin Kopyala

Paulowski L., Filip R., Makek M. J., Guglielmetti L., Goletti D., van Ingen J., ...Daha Fazla

PLoS ONE, cilt.19, sa.April, 2024 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 19 Sayı: April
Basım Tarihi: 2024
Doi Numarası: 10.1371/journal.pone.0291404
Dergi Adı: PLoS ONE
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Agricultural & Environmental Science Database, Animal Behavior Abstracts, Aquatic Science & Fisheries Abstracts (ASFA), BIOSIS, Biotechnology Research Abstracts, Chemical Abstracts Core, Food Science & Technology Abstracts, Index Islamicus, Linguistic Bibliography, MEDLINE, Pollution Abstracts, Psycinfo, zbMATH, Directory of Open Access Journals
Marmara Üniversitesi Adresli: Evet

Özet

We determined the impact of the COVID-19 pandemic on mycobacterial diagnostic services. 40 laboratories from 22 countries completed an online questionnaire covering the redeployment of the laboratory infrastructure and/or staff for SARS-CoV-2 testing, staff shortages and supply chain disruptions. 28 laboratories reported monthly numbers of samples processed for mycobacterial investigations and monthly numbers of M. tuberculosis complex (MTBC) PCRs performed between October 1st 2018 and October 31st 2020. More than half (23/40) of the participating TB laboratories reported having performed COVID-19 diagnostics in the early phase of the pandemic, in part with negative impact on the mycobacterial service activities. All participating laboratories reported shortages of consumables and laboratory equipment due to supply chain issues. Average monthly sample numbers decreased by 24% between January 2020 and October 2020 compared to pre-pandemic averages. At the end of the study period, most participating laboratories had not returned to pre-pandemic average MTBC PCR throughput.