Varicella-Zoster Virus Infection and Brivudine Therapy: Unexpected Response in Sarcoma Patient

KÖSTEK O., Sari M., BAYOĞLU İ. V.

EURASIAN JOURNAL OF MEDICINE AND ONCOLOGY, cilt.6, sa.2, ss.182-185, 2022 (ESCI) identifier identifier identifier

  • Yayın Türü: Makale / Editöre Mektup
  • Cilt numarası: 6 Sayı: 2
  • Basım Tarihi: 2022
  • Doi Numarası: 10.14744/ejmo.2022.26330
  • Dergi Adı: EURASIAN JOURNAL OF MEDICINE AND ONCOLOGY
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.182-185
  • Anahtar Kelimeler: VZV-infection, brivudine, undifferentiated pleomorphic sarcoma, anti-tumoral response, THYMIDINE KINASE 1
  • Marmara Üniversitesi Adresli: Evet

Özet

Soft tissue sarcoma is a heterogeneous disease and treatment options are limited in advanced stage settings. Brivudine is a thymidine-nucleoside analog and inhibits DNA polymerase in VZV infection. We demonstrated a case of a patient who was diagnosed with both VZV infection and advanced stage sarcoma, and unexpected anti-tumoral response after brivudine therapy.