Varicella-Zoster Virus Infection and Brivudine Therapy: Unexpected Response in Sarcoma Patient

KÖSTEK O., Sari M., BAYOĞLU İ. V.

EURASIAN JOURNAL OF MEDICINE AND ONCOLOGY, vol.6, no.2, pp.182-185, 2022 (ESCI, TRDizin) identifier identifier identifier

  • Publication Type: Article / Editorial Material
  • Volume: 6 Issue: 2
  • Publication Date: 2022
  • Doi Number: 10.14744/ejmo.2022.26330
  • Journal Name: EURASIAN JOURNAL OF MEDICINE AND ONCOLOGY
  • Journal Indexes: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Page Numbers: pp.182-185
  • Keywords: VZV-infection, brivudine, undifferentiated pleomorphic sarcoma, anti-tumoral response, THYMIDINE KINASE 1
  • Marmara University Affiliated: Yes

Abstract

Soft tissue sarcoma is a heterogeneous disease and treatment options are limited in advanced stage settings. Brivudine is a thymidine-nucleoside analog and inhibits DNA polymerase in VZV infection. We demonstrated a case of a patient who was diagnosed with both VZV infection and advanced stage sarcoma, and unexpected anti-tumoral response after brivudine therapy.