2-mercaptoethane sulfonate (MESNA) protects against biliary obstruction-induced oxidative damage in rats

Sener, GÖKSEL; Kabasakal, LEVENT; Sehirli, O; Ercan, FERİHA; Gedik, N

doi:10.1016/j.hepres.2006.02.009

2-mercaptoethane sulfonate (MESNA) protects against biliary obstruction-induced oxidative damage in rats

Atıf İçin Kopyala

Sener G., Kabasakal L., Sehirli O., Ercan F., Gedik N.

HEPATOLOGY RESEARCH, cilt.35, sa.2, ss.140-146, 2006 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 35 Sayı: 2
Basım Tarihi: 2006
Doi Numarası: 10.1016/j.hepres.2006.02.009
Dergi Adı: HEPATOLOGY RESEARCH
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.140-146
Marmara Üniversitesi Adresli: Evet

Özet

The aim of this study was to assess the antioxidant and antifibrotic effects of chronic administration of 2-mercaptoethane sulfonate (MESNA) on oxidative liver damage and fibrosis induced by biliary obstruction in rats. Liver fibrosis was induced in male Wistar albino rats by bile duct ligation and scission (BDL).