2-mercaptoethane sulfonate (MESNA) protects against biliary obstruction-induced oxidative damage in rats


Sener G. , Kabasakal L. , Sehirli O., Ercan F. , Gedik N.

HEPATOLOGY RESEARCH, cilt.35, ss.140-146, 2006 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 35 Konu: 2
  • Basım Tarihi: 2006
  • Doi Numarası: 10.1016/j.hepres.2006.02.009
  • Dergi Adı: HEPATOLOGY RESEARCH
  • Sayfa Sayıları: ss.140-146

Özet

The aim of this study was to assess the antioxidant and antifibrotic effects of chronic administration of 2-mercaptoethane sulfonate (MESNA) on oxidative liver damage and fibrosis induced by biliary obstruction in rats. Liver fibrosis was induced in male Wistar albino rats by bile duct ligation and scission (BDL).