Research Information System
in: Functionalized Nanomaterials for Biosensing and Bioelectronics Applications: Trends and Challenges, Elsevier, pp.251-270, 2024
Nanomaterials exhibit exceptional properties, including mechanical strength. Their physical and chemical superiority reduces the activation energy of reactions. In addition, they can be used to provide and enhance the immobilization of targeted biomolecules and allow for new signal transmission technologies in sensors. Nanomaterials can enhance biosensing performance, such as sensitivity, stability, and selectivity. Various cancer biomarkers are used to clinically diagnose cancers. Point-of-care devices for precise diagnostics are paramount for detecting multiple cancer biomarkers found in low concentrations in biological fluids. Biosensors, with their unique designs, fully satisfy the need to detect these biomarkers. Electrochemical, optical, mass, and immunoassay-based biosensors have been developed for various applications. This chapter summarizes the general concepts and studies of functionalized nanomaterial-based biosensors that have been performed in the literature.