Effect of sildenafil citrate in testosterone induced benign prostate hyperplasia rat model

Caliskan S., Keles M. O., Ozturk M. I., Kutluhan M. A., Tok O. E., ERCAN F., ...Daha Fazla

TURKISH JOURNAL OF UROLOGY, cilt.40, sa.4, ss.434-438, 2017 (ESCI) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 40 Sayı: 4
  • Basım Tarihi: 2017
  • Doi Numarası: 10.5152/tud.2017.23356
  • Dergi Adı: TURKISH JOURNAL OF UROLOGY
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.434-438
  • Marmara Üniversitesi Adresli: Evet

Özet

Objective: Efficacy of treatments for benign prostate hyperplasia (BPH) is limited because the disease has complex etiopathogenesis. Recent studies have demonstrated the presence of phosphodiesterase-5 (PDE-5) receptors in prostate tissue. We investigated efficacy of sildenafil citrate in testosteron -induced BPH in rats.