Effect of sildenafil citrate in testosterone induced benign prostate hyperplasia rat model

Caliskan, Selahattin; Keles, Muzaffer; Ozturk, Metin; Kutluhan, Musab; Tok, Olgu; ERCAN, FERİHA; Karaman, Muhammet

doi:10.5152/tud.2017.23356

Effect of sildenafil citrate in testosterone induced benign prostate hyperplasia rat model

Caliskan S., Keles M. O., Ozturk M. I., Kutluhan M. A., Tok O. E., ERCAN F., ...Daha Fazla

TURKISH JOURNAL OF UROLOGY, cilt.40, sa.4, ss.434-438, 2017 (ESCI)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 40 Sayı: 4
Basım Tarihi: 2017
Doi Numarası: 10.5152/tud.2017.23356
Dergi Adı: TURKISH JOURNAL OF UROLOGY
Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
Sayfa Sayıları: ss.434-438
Marmara Üniversitesi Adresli: Evet

Özet

Objective: Efficacy of treatments for benign prostate hyperplasia (BPH) is limited because the disease has complex etiopathogenesis. Recent studies have demonstrated the presence of phosphodiesterase-5 (PDE-5) receptors in prostate tissue. We investigated efficacy of sildenafil citrate in testosteron -induced BPH in rats.