Effect of stage 2 kindling on local cerebral blood flow rates in rats with genetic absence epilepsy


Carcak N., Ferrandon A., Koning E., Aker R., Oezdemir O., ONAT F., ...Daha Fazla

EPILEPSIA, cilt.50, sa.1, ss.33-43, 2009 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 50 Sayı: 1
  • Basım Tarihi: 2009
  • Doi Numarası: 10.1111/j.1528-1167.2008.01712.x
  • Dergi Adı: EPILEPSIA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.33-43
  • Anahtar Kelimeler: Limbic seizures, Epileptogenesis, Kindling-resistance, Spike-and-wave discharges, [C-14]-iodoantipyrine, ELECTRICAL-STIMULATION, ENTORHINAL CORTEX, WAVE DISCHARGES, TEMPORAL-LOBE, SEIZURES, MODEL, BRAIN, METABOLISM, MECHANISMS, GLUTAMATE
  • Marmara Üniversitesi Adresli: Evet

Özet

Genetic absence epilepsy rats from Strasbourg (GAERS) are resistant to the progression of kindling seizures. We studied local cerebral blood flow (LCBF) changes in brain regions involved in seizures in both GAERS and nonepileptic rats (NEC) to map the differences that may be related to the resistance to kindling.