Poly (methyl vinyl ether-co-maleic acid) - Pectin based hydrogel-forming systems: Gel, film, and microneedles

Demir Y. K., METİN A. Ü., Satiroglu B., Solmaz M. E., Kayser V., Maeder K.

EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, vol.117, pp.182-194, 2017 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 117
  • Publication Date: 2017
  • Doi Number: 10.1016/j.ejpb.2017.04.018
  • Journal Name: EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.182-194
  • Keywords: Pectin, Poly (methyl vinyl ether-maleic acid), Swelling kinetics, Microneedles, POLY(VINYL ALCOHOL), DELIVERY, WATER, NETWORK, DRUG, MISCIBILITY, ANHYDRIDE), PARAMETERS, MICROWAVE, BEHAVIOR
  • Marmara University Affiliated: Yes

Abstract

Cross-linking of natural and synthetic polymers is widely explored to achieve the desired material properties (mechanical strength, drug loading capacity, swelling and erosion rates). However, the potential of polymers produced by crosslinking poly (methyl vinyl ether-co-maleic acid) (PMVE/IVIA) and pectin (PE) in pharmaceutics is mainly unexplored so far.