Common Variants in the ATP-binding Cassette Transporter 1 Gene with Decreased HDL-Cholesterol Levels and Coronary Artery Disease


Catakoglu A. B. , Duman B. S. , Kurtoglu H., ERSÖZ M., Sener M., Celebi H., et al.

ARCHIVES OF MEDICAL RESEARCH, cilt.39, ss.735-742, 2008 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 39 Konu: 8
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1016/j.arcmed.2008.07.008
  • Dergi Adı: ARCHIVES OF MEDICAL RESEARCH
  • Sayfa Sayısı: ss.735-742

Özet

Background. Our aim was to determine whether the common variants within the coding sequence of ABCA1 gene affects low plasma high-density lipoprotein cholesterol (HDL-C) levels in Turkish patients with coronary artery disease (CAD). The study group was composed of 552 CAD patients, of which 251 had HDL-C levels <= 40 mg/dL, and 301 had HDL-C levels > 40 mg/dL.