A neuroanatomical comparison of humans and spotted hyena, a natural animal model for common urogenital sinus: Clinical reflections on feminizing genitoplasty

Baskin L., YÜCEL S., Cunha G., Glickman S., Place N.

JOURNAL OF UROLOGY, cilt.175, sa.1, ss.276-283, 2006 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 175 Sayı: 1
  • Basım Tarihi: 2006
  • Doi Numarası: 10.1016/s0022-5347(05)00014-5
  • Dergi Adı: JOURNAL OF UROLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.276-283
  • Marmara Üniversitesi Adresli: Hayır

Özet

Purpose: Surgical treatment of the common urogenital sinus phallus has been one of the most challenging areas in pediatric urology. To better understand the neuroanatomy of the common urogenital sinus phallus, we evaluated an animal model naturally having this condition, the spotted hyena, Crocuta crocuta. We compared the neuroanatomy of male and female humans and spotted hyenas using anatomical, immunohistochemical and 3D reconstruction techniques. We also examined the implications of the pattern of clitoral innervation for the unique challenges faced by female spotted hyenas, the only extant species of mammal that mates and gives birth through the clitoris.