The protective effect of oxytocin on renal ischemia/reperfusion injury in rats

Tugtepe, Halil; Sener, GÖKSEL; Biyikli, Nese; Yuksel, MERAL; Cetinel, ŞULE; Gedik, Nursal; Yegen, BERRAK

doi:10.1016/j.regpep.2006.11.026

The protective effect of oxytocin on renal ischemia/reperfusion injury in rats

Tugtepe H., Sener G., Biyikli N. K., Yuksel M., Cetinel S., Gedik N., ...Daha Fazla

REGULATORY PEPTIDES, cilt.140, sa.3, ss.101-108, 2007 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 140 Sayı: 3
Basım Tarihi: 2007
Doi Numarası: 10.1016/j.regpep.2006.11.026
Dergi Adı: REGULATORY PEPTIDES
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.101-108
Anahtar Kelimeler: oxytocin, ischemia/reperfusion, kidney, lipid peroxidation, myeloperoxidase, glutathione, ISCHEMIA-REPERFUSION INJURY, NITRIC-OXIDE SYNTHASE, NEUTROPHIL-DEPENDENT MECHANISM, ATRIAL-NATRIURETIC-PEPTIDE, ADHESION MOLECULES, FAILURE, RECEPTORS, KIDNEY, MYELOPEROXIDASE, INFLAMMATION
Marmara Üniversitesi Adresli: Evet

Özet

Aim: Oxytocin was previously shown to have anti-inflammatory effects in different inflammation models. The major objective of the present study was to evaluate the protective role of oxytocin (OT) in protecting the kidney against ischemia/reperfusion (I/R) injury.