Lipid peroxidation and paraoxonase activity in nocturnal cyclic and sustained intermittent hypoxia

Okur H. K., Pelin Z., YÜKSEL M., YOSUNKAYA Ş.

SLEEP AND BREATHING, cilt.17, sa.1, ss.365-371, 2013 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 17 Sayı: 1
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1007/s11325-012-0703-5
  • Dergi Adı: SLEEP AND BREATHING
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.365-371
  • Anahtar Kelimeler: Intermittent hypoxia, Obstructive sleep apnea, Chronic obstructive pulmonary disease, Paraoxonase, Lipid peroxidation, Oxidative stress, OBSTRUCTIVE SLEEP-APNEA, LOW-DENSITY-LIPOPROTEIN, 60 MM HG, PULMONARY-DISEASE, OXIDATIVE STRESS, LUNG-FUNCTION, ATHEROSCLEROSIS, ASSOCIATION, ACTIVATION, MORTALITY
  • Marmara Üniversitesi Adresli: Evet

Özet

Obstructive sleep apnea (OSA) and chronic obstructive pulmonary disease (COPD) have been known to be associated with atherosclerosis and hypoxia which was suggested to have an important role in this process by the way of increased oxidative stress. In the present study, we aimed to evaluate the effects of nocturnal hypoxia pattern (intermittent versus sustained) on serum lipid peroxidation and paraoxonase (PON) activity.