Metastatic Mucinous Adenocarcinoma of Unknown Origin Showing 68Ga-DOTATATE Uptake

Filizoglu N., ÖZGÜVEN S., DEDE F., TUROĞLU H. T., ERDİL T. Y.

Clinical Nuclear Medicine, 2024 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Basım Tarihi: 2024
  • Doi Numarası: 10.1097/rlu.0000000000005548
  • Dergi Adı: Clinical Nuclear Medicine
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE
  • Anahtar Kelimeler: 68Ga-DOTATATE PET/CT, metastasis, mucinous adenocarcinoma, nonneuroendocrine tumors
  • Marmara Üniversitesi Adresli: Evet

Özet

Although the use of 18F-FDG PET/CT is well established in the evaluation of adenocarcinoma, the performance of 18F-FDG PET/CT in mucinous adenocarcinoma is not consistent. 68Ga-DOTATATE uptake can be observed in some non-neuroendocrine tumors as a result of tumor blood flow and somatostatin receptor expression at different levels. For this reason, 68Ga-DOTATATE PET/CT may have a prospective role in the evaluation of mucinous adenocarcinoma. However, there is no published case of mucinous adenocarcinoma with 68Ga-DOTATATE uptake. We present a unique case of metastatic mucinous adenocarcinoma of unknown origin on 68Ga-DOTATATE PET/CT.