Riboflavin Treatment Reduces Apoptosis and Oxidative DNA Damage in a Rat Spinal Cord Injury Model

Sakarcan, Sinem; ERŞAHİN, MEHMET; Eminoglu, Mehmet; ÇEVİK, ÖZGE; AK, ESİN; ERCAN, FERİHA; ŞENER, GÖKSEL

doi:10.5152/clinexphealthsci.2017.218

Riboflavin Treatment Reduces Apoptosis and Oxidative DNA Damage in a Rat Spinal Cord Injury Model

Sakarcan S., ERŞAHİN M., Eminoglu M. E., ÇEVİK Ö., AK E., ERCAN F., ...Daha Fazla

CLINICAL AND EXPERIMENTAL HEALTH SCIENCES, cilt.7, sa.2, ss.55-63, 2017 (ESCI)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 7 Sayı: 2
Basım Tarihi: 2017
Doi Numarası: 10.5152/clinexphealthsci.2017.218
Dergi Adı: CLINICAL AND EXPERIMENTAL HEALTH SCIENCES
Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
Sayfa Sayıları: ss.55-63
Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
Marmara Üniversitesi Adresli: Evet

Özet

Objective: Spinal cord injury (SCI) leads to an inflammatory response and results in oxidative stress, which has deleterious effects on several organ systems. Riboflavin is an easily absorbed micronutrient that plays an important role in maintaining health in humans and animals. The present study was designed to investigate the putative protective effect of riboflavin against SCI-induced spinal cord and kidney damage.