Alliance of Molar Incisor Hypomineralization Investigation and Treatment (AMIT), Munich, Almanya, 30 Kasım - 03 Aralık 2022, ss.17-18, (Özet Bildiri)
Background/Aim: Enamel defects and dental caries in children with systemic disease are quite important for public health, since they can identify possible etiological factors, as well as identifying populations that merit priority preventive interventions. The aim of the study was to investigate the molar incisor hypomineralization and dental caries in children with different stages of CKD and kidney transplant recipients (KTR), as well as compare it with a group of healthy children.
Method: A total of seventy-one children aged between 0-18 years diagnosed with CKD or KTR and fifty-two healthy children were included in the study. Each patient was examined for dental caries by the International Caries Detection and Assessment System (ICDAS-II) criteria and molar incisor hypomineralization (MIH) by the modified DDE (mDDE)index. Fisher exact test for comparing quantitative variables between groups were used. p< 0.05 was considered statistically significant.
Results: The stage 1-3 and 4-5 of CKD patients had statistically significant lower caries scores than the healthy children (p < 0.05). According to ICDAS-II subgroups, there was a statistically significant difference between stage 4-5 patients and healthy children (p < 0.001). Enamel defects were observed in 4 out of 5 stage 4-5 patients. The higher rate of MIH lesions observed in stage 4-5 patients (p = 0.001) and these lesions was also higher in children with KTR than healthy children (p < 0.001). ICDAS-II and mDDE categories were statistically significantly different between all groups (p <0.001 and p < 0.001).
Conclusion: According to our study, the incidence of MIH-related lesions were found to be higher in children with advanced CKD while the risk of dental caries was found to be lower. We conclude that CKD affect enamel formation and suggest a need for further studies of the etiological factors involved in chidren with CKD.
Keywords: Molar incisor hypomineralization, chronic kidney disease, kidney transplant recipients, dental caries