Linezolid treatment of shunt-related cerebrospinal fluid infections in children Clinical article

Yilmaz A., Dalgic N., Musluman M., SANCAR M. , Colak I., Aydin Y.

JOURNAL OF NEUROSURGERY-PEDIATRICS, cilt.5, sa.5, ss.443-448, 2010 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 5 Konu: 5
  • Basım Tarihi: 2010
  • Doi Numarası: 10.3171/2009.12.peds09421
  • Sayfa Sayıları: ss.443-448


Object. The emergence of multidrug-resistant bacteria as a cause of ventriculoperitoneal (VP) shunt infection is a disconcerting phenomenon that often requires the use of alternative antimicrobial agents due to resistance against commonly used medications. Linezolid, a member of a new class of antimicrobial agents, has good activity against virtually all important gram-positive pathogens, including multidrug-resistant gram-positive pathogens. The object of this article is to report a single-center experience with linezolid treatment in 6 young patients with VP shunt infections caused by drug-resistant strains.