The Research Domain Criteria framework: transitioning from dimensional systems to integrating neuroscience and psychopathology

KÖSE A., Cetin M.

PSYCHIATRY AND CLINICAL PSYCHOPHARMACOLOGY, cilt.27, sa.1, ss.1-5, 2017 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Editöre Mektup
  • Cilt numarası: 27 Sayı: 1
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1080/24750573.2017.1293255
  • Dergi Adı: PSYCHIATRY AND CLINICAL PSYCHOPHARMACOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1-5
  • Anahtar Kelimeler: RDoC, neuroscience, psychiatric diagnosis, psychiatric treatment, PSYCHOTIC SYMPTOMS, SCHIZOPHRENIA, HETEROGENEITY
  • Marmara Üniversitesi Adresli: Hayır

Özet

Although recent research in neuroscience and genetics is providing new insights into the etiology of psychiatric disorders, progress in treatment development has been hindered by reliance on diagnostic categories that are based primarily on presenting signs and symptoms. The NIMH Research Domain Criteria (RDoC) framework seeks to provide a neuroscience-based nosological background for future research on psychopathology, categorizing individuals for research purposes using a dimensional approach that benefit from significant progress in modern neuroscience. These scientific advances combined with new approaches to classification can inform the development of novel, circuit-based interventions and the personalization of treatments available. In this editorial, we describe the RDoC framework compared with Diagnostic and Statistical Manual/International Classification of Disease systems and highlight some of the emerging progress in RDoC-based research that is consistent with these developments.