Reference values for serum dehydroepiandrosterone-sulphate in healthy children and adolescents with emphasis on the age of adrenarche and pubarche

Guran T., Firat I., Yildiz F., Bulut I. K., Dogru M., Bereket A.

CLINICAL ENDOCRINOLOGY, vol.82, no.5, pp.712-718, 2015 (SCI-Expanded) identifier

  • Publication Type: Article / Article
  • Volume: 82 Issue: 5
  • Publication Date: 2015
  • Doi Number: 10.1111/cen.12612
  • Journal Name: CLINICAL ENDOCRINOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.712-718
  • Marmara University Affiliated: Yes

Abstract

ObjectiveAdrenarche is a component of normal pubertal development. Recent decades have witnessed changes in the timing and tempo of puberty in different populations. We aimed to obtain normative data on dehydroepiandrosterone-sulphate (DHEA-S) secretion in healthy children and to evaluate the age of adrenarche, pubarche and the DHEA-S levels at which pubarche starts in both sexes.