Estrogen protects the liver and intestines against sepsis-induced injury in rats

Sener G., Arbak S., Kurtaran P., Gedik N., Yegen B.

JOURNAL OF SURGICAL RESEARCH, cilt.128, sa.1, ss.70-78, 2005 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 128 Sayı: 1
  • Basım Tarihi: 2005
  • Doi Numarası: 10.1016/j.jss.2005.02.019
  • Dergi Adı: JOURNAL OF SURGICAL RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.70-78
  • Anahtar Kelimeler: estrogens, lipid peroxidation, glutathione, TNF-alpha, sepsis, LIPID-PEROXIDATION, MELATONIN TREATMENT, FREE-RADICALS, SEX-HORMONES, BURN INJURY, ANTIOXIDANT, GLUTATHIONE, STEROIDS, FAILURE, SHOCK
  • Marmara Üniversitesi Adresli: Evet

Özet

Background and aim. Sepsis is commonly associated with enhanced generation of reactive oxygen metabolites, leading to multiple organ dysfunctions. The aim of this study was to examine the putative protective role of estradiol against sepsis-induced oxidative organ damage.