The effects of pulsatile cardiopulmonary bypass on acute kidney injury

Adademir T., AK K. , Aljodi M., Elci M. E. , ARSAN S. , Isbir S.

INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS, vol.35, no.7, pp.511-519, 2012 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 35 Issue: 7
  • Publication Date: 2012
  • Doi Number: 10.5301/ijao.5000097
  • Title of Journal : INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS
  • Page Numbers: pp.511-519
  • Keywords: Neutrophil gelatinase-associated lipocalin, NGAL, Interleukin-18, IL-18, Cardiopulmonary Bypass, Cardiac surgery, GELATINASE-ASSOCIATED LIPOCALIN, PEDIATRIC HEART-SURGERY, NEONATAL PIGLET MODEL, VITAL ORGAN RECOVERY, ACUTE RENAL INJURY, CARDIAC-SURGERY, NONPULSATILE PERFUSION, INTRAAORTIC BALLOON, BLOOD-FLOW, DYSFUNCTION

Abstract

Purpose: Protective effect of pulsatile flow cardiopulmonary bypass (CPB) on the occurrence of acute renal injury is still a matter of debate. The objective of this study was to compare the effects of pulsatile and non-pulsatile cardiopulmonary bypass on kidneys using Urinary neutrophil gelatinase-associated lipocalin (NGAL) and interleukin-18 (IL-18) as the markers of renal injury.