The effects of pulsatile cardiopulmonary bypass on acute kidney injury

Adademir T., AK K., Aljodi M., Elci M. E., ARSAN S., Isbir S.

INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS, vol.35, no.7, pp.511-519, 2012 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 35 Issue: 7
  • Publication Date: 2012
  • Doi Number: 10.5301/ijao.5000097
  • Journal Name: INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.511-519
  • Keywords: Neutrophil gelatinase-associated lipocalin, NGAL, Interleukin-18, IL-18, Cardiopulmonary Bypass, Cardiac surgery, GELATINASE-ASSOCIATED LIPOCALIN, PEDIATRIC HEART-SURGERY, NEONATAL PIGLET MODEL, VITAL ORGAN RECOVERY, ACUTE RENAL INJURY, CARDIAC-SURGERY, NONPULSATILE PERFUSION, INTRAAORTIC BALLOON, BLOOD-FLOW, DYSFUNCTION
  • Marmara University Affiliated: Yes

Abstract

Purpose: Protective effect of pulsatile flow cardiopulmonary bypass (CPB) on the occurrence of acute renal injury is still a matter of debate. The objective of this study was to compare the effects of pulsatile and non-pulsatile cardiopulmonary bypass on kidneys using Urinary neutrophil gelatinase-associated lipocalin (NGAL) and interleukin-18 (IL-18) as the markers of renal injury.