Design and manufacture of hybrid mesh for hernia treatment


Saltik D., YÜKSEK M.

Journal of the Textile Institute, 2024 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Basım Tarihi: 2024
  • Doi Numarası: 10.1080/00405000.2024.2327118
  • Dergi Adı: Journal of the Textile Institute
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Applied Science & Technology Source, Compendex, INSPEC
  • Anahtar Kelimeler: centrifugal spinning, curcumin, Mesh structure, silk fibroin, warp-knit
  • Marmara Üniversitesi Adresli: Evet

Özet

The warp knitting method is typically used to create hernia mesh. It can add new qualities to the meshes due to the formation of micro/nanofibers, cell proliferation, biocompatibility, non-adhesion, and drug release properties. Within the purview of this work, warp-knitted mesh (polypropylene) with micro/nanofibers was created. On this constructed mesh structure, silk fibroin/polyurethane/levan/curcumin fibers were produced using the centrifugal jet spinning technique. When SEM images were examined, the average fiber diameter was 932 ± 407 nm, and the pore diameter was 20 µm. The nanofiber warp-knitted fabric was measured to have a bursting strength of 182.9 ± 11 kPa. It was determined that the abdominal wall’s predicted elasticity value of 15.65% horizontally was enough for both men and women. It was determined that the hybrid mesh structure performed better against E.coli bacteria and that the curcumin-infused mesh had an antibacterial effect. It was found that meshes might be employed as hybrid meshes for the treatment of hernias.