Atom-Economical Synthesis of Complex Heterocycles with N-O Moiety


Merey G., Sezen G.

HELVETICA CHIMICA ACTA, vol.98, no.9, pp.1315-1324, 2015 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 98 Issue: 9
  • Publication Date: 2015
  • Doi Number: 10.1002/hlca.201500076
  • Journal Name: HELVETICA CHIMICA ACTA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1315-1324
  • Marmara University Affiliated: No

Abstract

A concise and facile method for the synthesis of heterocyclic compounds with N-O tether was introduced. The two important steps of the synthesis are a Mitsunobu reaction and C-H activation. The Mitsunobu protocol allows to form the N-O moiety in the molecule, while subsequent C-H activation leads to heterocycles.