Out-of-Reference Range Thyroid-Stimulating Hormone Levels in Levothyroxine-Treated Primary Hypothyroid Patients: A Multicenter Observational Study

YAVUZ D., Yazici D., Keskin L., ATMACA A., Sancak S., Sarac F., ...Daha Fazla

FRONTIERS IN ENDOCRINOLOGY, cilt.8, 2017 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 8
  • Basım Tarihi: 2017
  • Doi Numarası: 10.3389/fendo.2017.00215
  • Dergi Adı: FRONTIERS IN ENDOCRINOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Anahtar Kelimeler: hypothyroidism, levothyroxine, target thyroid-stimulating hormone, thyroid-stimulating hormone, primary hypothyroidism, compliance, L-THYROXINE, PYLORI INFECTION, ABSORPTION, THERAPY, DISEASE, REPLACEMENT, PREVALENCE, COMMUNITY
  • Marmara Üniversitesi Adresli: Evet

Özet

Objective: Although levothyroxine (LT4) replacement therapy for hypothyroidism has been established as safe, inexpensive and effective, many studies from different countries reported out-of-reference range thyroid-stimulating hormone (TSH) values for the hypothyroid patients under LT4 treatment. The aim of this study was to determine TSH levels of primary hypothyroid patients under LT4 treatment and to assess self-reported compliance with daily LT4 intake in tertiary care centers in Turkey.