Research Information System
Nature Conferences-Bio-inspired Nanomaterials, Seoul, South Korea, 15 - 17 November 2021, pp.308, (Summary Text)
Graphene and its derivatives are promising materials for biomedical applications, particularly for wound dressing. One of most studied graphene derivatives in bioapplications is graphene oxide (GO), mainly as it is hydrophilic and stable in physiological solutions. Reduced graphene oxide (RGO) is the form of GO whose oxygen content is reduced by chemical, thermal and other methods. Since the most of the chemical reducing agents are highly toxic and dangerous, green reduction methods are developed and environmentally friendly and non-toxic reducing agents, such as plant extracts, microorganisms etc., are employed. In this study, GO was produced by a modified
Hummer’s method. Laurus nobilis extract was employed as reducing agent and it was contacted with GO to remove functional groups. GO and RGO were incorporated into
carboxymethyl cellulose/ polyethylene glycol (CMC/PEG) hydrogels with changing amounts to improve physical and chemical properties of hydrogels and considered as
potential wound dressings. Prepared hydrogels were characterized by FTIR for chemical structure determination. Morphological structures were examined from SEM micrographs. Swelling capacity of the hydrogels determined. Results showed that hydrogels prepared by GO and RGO has promising potential to be used for wound healing by
improving physical/chemical character of the hydrogel and material-cell interaction.