FK506 to prevent lung injury after hindlimb ischemia and reperfusion in a rat model: An electron microscopic study


Akgun S., Tekeli A., Isbir S., Civelek A., Ak K., Sirvanci S., ...Daha Fazla

SURGERY TODAY, cilt.34, sa.8, ss.678-684, 2004 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 34 Sayı: 8
  • Basım Tarihi: 2004
  • Doi Numarası: 10.1007/s00595-004-2799-0
  • Dergi Adı: SURGERY TODAY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.678-684
  • Marmara Üniversitesi Adresli: Evet

Özet

Purpose. Hindlimb ischemia and reperfusion leads to lung injury in various animal models. We investigated the effectiveness of FK506, an immunosuppressive agent, which also modulates neutrophilic infiltration, in preventing lung injury after hindlimb ischemia and reperfusion in a rat model.