The antioxidant and anti-inflammatory efficiency of hyaluronic acid after third molar extraction

GÖÇMEN G., GÖNÜL O., OKTAY N. Ş., YARAT A., Goker K.

JOURNAL OF CRANIO-MAXILLOFACIAL SURGERY, vol.43, no.7, pp.1033-1037, 2015 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 43 Issue: 7
  • Publication Date: 2015
  • Doi Number: 10.1016/j.jcms.2015.04.022
  • Journal Name: JOURNAL OF CRANIO-MAXILLOFACIAL SURGERY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1033-1037
  • Keywords: Hyaluronic acid, Third molar extraction, Wound healing, DAMAGE, SURGERY, REPAIR, TISSUE
  • Marmara University Affiliated: Yes

Abstract

Purpose: Hyaluronic acid (HA) has a number of clinical applications in current practice. Therefore, correlation of HA with free radicals and inflammatory cells is clinically important. The purpose of this study is to measure the efficacy of high molecular weight HA on the oxidative stress of oral wounds (glutathione (GSH) and lipid peroxidation (LPO) levels), the inflammatory reaction (leucocytes, collagen and angiogenesis content), pain (visual analogue scale (VAS) records) and trismus (maximum interincisal opening (MIO) records) after third molar (M3) extraction.