Expression of Angiogenic Factors in Craniopharyngiomas: Implications for Tumor Recurrence


Sun H. I., Akgun E., Bicer A., Ozkan A., Bozkurt S. U., Kurtkaya O., ...Daha Fazla

NEUROSURGERY, cilt.66, sa.4, ss.744-750, 2010 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 66 Sayı: 4
  • Basım Tarihi: 2010
  • Doi Numarası: 10.1227/01.neu.0000367553.65099.14
  • Dergi Adı: NEUROSURGERY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.744-750
  • Marmara Üniversitesi Adresli: Evet

Özet

BACKGROUND: The primary treatment for craniopharyngiomas is total excision, but recurrence is common. However, current knowledge on the mechanisms of recurrence is limited. OBJECTIVE: We hypothesized that recurrence is linked to the angiogenesis of the tumor. Recurrent and nonrecurrent tumor samples were compared with regard to expression of angiogenesis-related factors and angiogenic capacity in a corneal angiogenesis model.