Expression of Angiogenic Factors in Craniopharyngiomas: Implications for Tumor Recurrence


Sun H. I. , Akgun E., Bicer A., Ozkan A., Bozkurt S. U. , Kurtkaya O., ...Daha Fazla

NEUROSURGERY, cilt.66, ss.744-750, 2010 (SCI İndekslerine Giren Dergi) identifier identifier identifier

Özet

BACKGROUND: The primary treatment for craniopharyngiomas is total excision, but recurrence is common. However, current knowledge on the mechanisms of recurrence is limited. OBJECTIVE: We hypothesized that recurrence is linked to the angiogenesis of the tumor. Recurrent and nonrecurrent tumor samples were compared with regard to expression of angiogenesis-related factors and angiogenic capacity in a corneal angiogenesis model.