Comparison of Bone Prefabrication with Vascularized Periosteal Flaps, Hydroxyapatite, and Bioactive Glass in Rats


ERSOY B., Bayramicli M. , ERCAN F. , Sirinoglu H., Turan P., Numanoglu A.

JOURNAL OF RECONSTRUCTIVE MICROSURGERY, vol.31, no.4, pp.291-299, 2015 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 31 Issue: 4
  • Publication Date: 2015
  • Doi Number: 10.1055/s-0034-1396770
  • Title of Journal : JOURNAL OF RECONSTRUCTIVE MICROSURGERY
  • Page Numbers: pp.291-299
  • Keywords: hydroxyapatite, bioactive glass, periosteum, rats, osteogenesis, MORPHOGENETIC PROTEIN, AUTOGENOUS BONE, GRAFTS, DEFECTS, CEMENT

Abstract

Background Periosteal flaps possess osteoprogenitor cells and an osteoinductive potential that can be further augmented by combination with a biodegradable scaffold; therefore, various osteoconductive and osteostimulative biomaterials are frequently combined with periosteal flaps in studies of bone prefabrication. An experimental study was designed to determine and compare the contribution of bioactive glass and hydroxyapatite to osteoneogenesis in rats when combined with a periosteal flap.