New Dithiophosphonato Ni(II) Complexes: Synthesis, characterization, theoretical and in vitro cytotoxicity studies

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Atıf İçin Kopyala

Bulat E., Sağlam E. G., Akkoç S., Zeyrek C. T., Zorlu Y.

Frühjahrssymposium 2023, Giessen, Almanya, 21 - 24 Şubat 2023, ss.1

• Yayın Türü: Bildiri / Özet Bildiri
• Basıldığı Şehir: Giessen
• Basıldığı Ülke: Almanya
• Sayfa Sayıları: ss.1
• Marmara Üniversitesi Adresli: Evet

Özet

Dithiophosphonic acids (DTFOA), one of the compounds of the organo-dithiophosphorus group, have been preferred more in studies because they are easier to synthesize and have higher yields than other organo-dithiophosphorus compounds. DTFOA's are converted to derivatives due to the bad smell of the crude acid formed at the end of the reaction^[1,2].

In this study; New Ni(II) complexes were synthesized from the synthesized dithiophosphonic acid salts. Structures of synthesized four-coordinated Ni(II) complexes were elucidated by various spectroscopic methods. In addition, were made by single crystal X-ray diffraction analysis as well as theoretical and molecular docking studies. The in vitro cytotoxic activity of the compounds was studied.