New Dithiophosphonato Ni(II) Complexes: Synthesis, characterization, theoretical and in vitro cytotoxicity studies
Frühjahrssymposium 2023, Giessen, Almanya, 21 - 24 Şubat 2023, ss.1, (Özet Bildiri)
- Yayın Türü: Bildiri / Özet Bildiri
- Basıldığı Şehir: Giessen
- Basıldığı Ülke: Almanya
- Sayfa Sayıları: ss.1
- Marmara Üniversitesi Adresli: Evet
Özet
Dithiophosphonic
acids (DTFOA), one of the compounds of the organo-dithiophosphorus group, have
been preferred more in studies because they are easier to synthesize and have higher
yields than other organo-dithiophosphorus compounds. DTFOA's are converted to
derivatives due to the bad smell of the crude acid formed at the end of the
reaction[1,2].
In
this study; New Ni(II) complexes were synthesized from the synthesized dithiophosphonic
acid salts. Structures of synthesized four-coordinated Ni(II) complexes were elucidated
by various spectroscopic methods. In addition, were made by single crystal
X-ray diffraction analysis as well as theoretical and molecular docking
studies. The in vitro cytotoxic activity of the compounds was studied.