Animal models of asthma

AKKOÇ T.

MARMARA PHARMACEUTICAL JOURNAL, cilt.14, sa.3, ss.104-111, 2010 (ESCI) identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 14 Sayı: 3
  • Basım Tarihi: 2010
  • Doi Numarası: 10.12991/201014444
  • Dergi Adı: MARMARA PHARMACEUTICAL JOURNAL
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus
  • Sayfa Sayıları: ss.104-111
  • Anahtar Kelimeler: Asthma, Mouse, Ovalbumin, Regulatory cells, REGULATORY T-CELLS, ALLERGIC AIRWAY INFLAMMATION, MURINE MODEL, IMMUNE DYSREGULATION, TOLERANCE INDUCTION, LUNG INFLAMMATION, MOUSE MODELS, FOXP3, INTERLEUKIN-10, IL-10
  • Marmara Üniversitesi Adresli: Evet

Özet

Allergic disease such as asthma, rhinitis, and eczema are increasing prevelance and affect up to 15% of population in Westernized countries. Among them, asthma is a chronic inflammatory disease of airways and the underlying physiological and immunological processes are not fully understood. Mouse models of asthma dupicates many features of human asthma, including airway hyperreactivity, andairway inflammation. Therefore, relevant models for asthma are important to understand the mechanism of disease and therapeutical approach. In this article, basicly various animal models of asthma and some theraputic approaches are disscussed.