Cytotoxic Antibody Detection by Means of Flow-Cytometric Cross-Match

Bilgen T., Ata P. , Tozkir J., Tozkir H., Titiz M. I.

TRANSPLANTATION PROCEEDINGS, cilt.49, sa.3, ss.440-444, 2017 (SCI İndekslerine Giren Dergi) identifier identifier identifier


Background. Complement-dependent lymphocytotoxicity (CDC-XM) and flowcytometric (FCXM) cross-match are analyzed individually for each donor and recipient pair, because these techniques have fundamental differences for the evaluation of histocompatibility. Lately, cytotoxic flow-cytometric cross-match (cFCXM) has been developed as an alternative to both CDC-XM and FCXM techniques. We evaluated the limits of cFCXM with the use of different positive serum dilutions.