Capillary leak syndrome in a 5-month-old infant associated with intractable diarrhoea

Onal H., Aktuglu-Zeybek C., Altun G., Ozyilmaz I., Alhaj S., Aydin A.

ANNALS OF TROPICAL PAEDIATRICS, cilt.27, sa.1, ss.81-86, 2007 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 27 Sayı: 1
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1179/146532807x170556
  • Dergi Adı: ANNALS OF TROPICAL PAEDIATRICS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.81-86
  • Marmara Üniversitesi Adresli: Hayır

Özet

Systemic capillary leak syndrome (SCLS) is a rare disorder of unknown pathophysiology, characterised by episodic life-threatening hypotension, haemoconcentration and hypo-albuminaemia. A 5-month-old child presented with episodes of relapsing diarrhoea, vomiting and hyponatraemia and developed generalised oedema during treatment. Clinical and laboratory findings were consistent with acute SCLS. Treatment with careful fluid replacement, fresh frozen plasma and aminophylline in the acute phase and teophylline and gingko biloba in the chronic phase led to sustained remission during follow-up for over I year. To our knowledge, this is the youngest case of SCLS in the literature and is unusual in that it presented with diarrhoea.