Fractional Anisotropic Changes of Corpus Callosum Associated with Antipsychotic Treatment in First-Episode Antipsychotic Drug-Naive Patients with Schizophrenia


Pan E., Ates M. A., Algul A., Aytekin A., Basoglu C., Ebrinc S., ...Daha Fazla

KLINIK PSIKOFARMAKOLOJI BULTENI-BULLETIN OF CLINICAL PSYCHOPHARMACOLOGY, cilt.26, sa.4, ss.332-341, 2016 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 26 Sayı: 4
  • Basım Tarihi: 2016
  • Doi Numarası: 10.5455/bcp.20160319021659
  • Dergi Adı: KLINIK PSIKOFARMAKOLOJI BULTENI-BULLETIN OF CLINICAL PSYCHOPHARMACOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.332-341
  • Anahtar Kelimeler: First-episode schizophrenia, fractional anisotropy, antipsychotic treatment, corpus callosum, WHITE-MATTER MICROSTRUCTURE, DIFFUSION TENSOR, INTEGRITY, DYSCONNECTIVITY, ABNORMALITIES, PSYCHOSIS
  • Marmara Üniversitesi Adresli: Hayır

Özet

Objective: Schizophrenia involves white matter abnormalities that might have a central role in the pathophysiology. Abnormal brain connectivity especially in prefrontal and temporal heteromodal cortex has been suggested as the leading structural impairment in patients with schizophrenia. In this study we examined the relationship between potential white matter changes and clinical response, as well as associations with antipsychotic treatment follow-up.