Fractional Anisotropic Changes of Corpus Callosum Associated with Antipsychotic Treatment in First-Episode Antipsychotic Drug-Naive Patients with Schizophrenia

Pan, Erdal; Ates, Mehmet; Algul, Ayhan; Aytekin, Aykut; Basoglu, Cengiz; Ebrinc, Servet; Cetin, Mesut; KÖSE, ABDÜSSAMED

doi:10.5455/bcp.20160319021659

Fractional Anisotropic Changes of Corpus Callosum Associated with Antipsychotic Treatment in First-Episode Antipsychotic Drug-Naive Patients with Schizophrenia

Pan E., Ates M. A. , Algul A., Aytekin A., Basoglu C., Ebrinc S., ...Daha Fazla

KLINIK PSIKOFARMAKOLOJI BULTENI-BULLETIN OF CLINICAL PSYCHOPHARMACOLOGY, cilt.26, sa.4, ss.332-341, 2016 (SCI İndekslerine Giren Dergi)

Cilt numarası: 26 Konu: 4
Basım Tarihi: 2016
Doi Numarası: 10.5455/bcp.20160319021659
Dergi Adı: KLINIK PSIKOFARMAKOLOJI BULTENI-BULLETIN OF CLINICAL PSYCHOPHARMACOLOGY
Sayfa Sayıları: ss.332-341

Özet

Objective: Schizophrenia involves white matter abnormalities that might have a central role in the pathophysiology. Abnormal brain connectivity especially in prefrontal and temporal heteromodal cortex has been suggested as the leading structural impairment in patients with schizophrenia. In this study we examined the relationship between potential white matter changes and clinical response, as well as associations with antipsychotic treatment follow-up.