Topical drug delivery using chitosan nano- and microparticles


SEZER A. D. , Cevher E.

EXPERT OPINION ON DRUG DELIVERY, cilt.9, ss.1129-1146, 2012 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 9 Konu: 9
  • Basım Tarihi: 2012
  • Doi Numarası: 10.1517/17425247.2012.702752
  • Dergi Adı: EXPERT OPINION ON DRUG DELIVERY
  • Sayfa Sayıları: ss.1129-1146

Özet

Introduction: Topical drug delivery offers important benefits for improving the therapeutic effect and reducing systemic side effects of the administered compounds. In addition, utilization of biopolymeric material-based systems can play a key role in developing new topical dosage forms and their applications. This review describes the advances that have been made, new strategies and as well as possible challenges of particular systems of chitosan used in topical drug delivery, including challenging innovations in topical usage of these systems that can make significant impact on clinical practice.