Akademik Veri Yönetim Sistemi
Microchemical Journal, cilt.215, 2025 (SCI-Expanded)
Global problems such as environmental pollution, food safety and human health have increased the need for low-cost, sensitive and selective detection systems. Electrochemical sensors stand out in this field thanks to their advantages such as fast response time, portability and high sensitivity. In this context, phthalocyanines (Pcs) and especially metal complexes (MPcs) attract attention as effective sensor materials due to their exceptional redox activity, chemical stability and ease of structural modified through central or peripheral substitutions. This review systematically evaluates MPc based electrochemical sensors from an analyte-specific perspective, focusing on targets such as glucose, dopamine, hydrogen peroxide, uric acid, pesticides, and toxic metal ions. How MPcs can be structurally customized through central metal ions and peripheral groups, the effects of these structural changes on basic performance parameters such as selectivity, detection limit, stability and sensitivity have been evaluated in detail. In addition, the contributions of hybrid MPc platforms created with nanostructures such as carbon nanotubes, graphene and metal oxides on the electrochemical performance have been extensively discussed. This study is not only material based; it presents a review that is application-oriented and considered from the perspective of target analytics. In addition, the potential of MPc based systems in the field of environmental monitoring and pollution detection was evaluated and the advantages and possible difficulties of phthalocyanine sensors were discussed. Finally, it also provides a guiding understanding for the potential applications of these systems in the future in emerging areas such as multi-analyte sensing, wearable sensor platforms and sustainable material integration.