Leukotriene D4 receptor antagonist montelukast alleviates protamine sulphate-induced changes in rat urinary bladder

ÇETİNEL Ş., Canillioglu Y. E., Cikler E., ŞENER G., ERCAN F.

BJU INTERNATIONAL, cilt.107, sa.8, ss.1320-1325, 2011 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 107 Sayı: 8
  • Basım Tarihi: 2011
  • Doi Numarası: 10.1111/j.1464-410x.2010.09532.x
  • Dergi Adı: BJU INTERNATIONAL
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1320-1325
  • Anahtar Kelimeler: protamine sulphate, interstitial cystitis, uroplakin, mast cell, tight junction, montelukast, INTERSTITIAL CYSTITIS, SURFACE GLYCOSAMINOGLYCANS, PERMEABILITY, ARTHRITIS, ASTHMA, MODEL
  • Marmara Üniversitesi Adresli: Evet

Özet

The mastocytosis in detrusor muscle and the leaky epithelium in interstitial cystitis were the most studied features. In this study the leaky epithelium was shown using the ruthenium red staining in electron microscopy and uroplakin distribution in light microscopy besides the mast cell concentration in detrusor muscle using tryptase immunohistochemistry.