Akademik Veri Yönetim Sistemi
International Journal of Urology, cilt.3, sa.6, ss.459-461, 1996 (Scopus)
Background: We compared preoperative tumor location, as identified by transrectal ultrasonography (TRUS), and TRUS-guided core biopsies with the final histopathological examination of radical prostatectomy specimens. Methods: Thirty patients who had radical retropubic prostatectomy after evaluation with TRUS are included in the study. Diagnosis of prostate cancer was established with TRUS-guided systematic (3 cores from base, mid and apex of the peripheral zone, and 1 core from the transition zone of each side of the prostate) and lesion-directed core biopsies in all cases. Each prostate gland was halved for histopathological examination and results are reported in terms of 'sides'. Results: Histopathological examination of the prostatectomy specimens revealed prostate cancer bilaterally in 29 glands (58 sides) and unilaterally in 1 gland. Preprostatectomy TRUS examinations missed cancer in 29 sides, and core biopsies were negative for cancer in 14 sides. Conclusion: This study revealed that 49% of prostate cancer lesions (n = 29 sides) were not recognized on TRUS and 52% of those (n = 15 sides). were diagnosed only by additional systematic biopsies. Furthermore, even with TRUS-guided systematic core biopsies, failure to detect the prostate cancer lesions may be as high as 24% (n = 14 sides).