Relationship between systemic immune-inflammation index and no-reflow in percutaneous coronary intervention for saphenous grafts

Demirci G., ŞAHİN A. A., Aktemur T., Demir A. R., Çetin İ., Karakurt H., ...Daha Fazla

Biomarkers in Medicine, cilt.17, sa.8, ss.427-435, 2023 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 17 Sayı: 8
  • Basım Tarihi: 2023
  • Doi Numarası: 10.2217/bmm-2023-0208
  • Dergi Adı: Biomarkers in Medicine
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Chemical Abstracts Core, EMBASE, MEDLINE
  • Sayfa Sayıları: ss.427-435
  • Anahtar Kelimeler: acute coronary syndrome, no-reflow, percutaneous coronary intervention, saphenous venous graft disease, SII
  • Marmara Üniversitesi Adresli: Evet

Özet

Objective: In this study, we investigated the occurrence of no-reflow (NR) in percutaneous coronary intervention (PCI) for saphenous vein grafts (SVGs) and its relationship with a new systemic immune-inflammation index (SII) that determines inflammation. Methods: We studied 303 patients with acute coronary syndrome without ST elevation who underwent PCI for SVG disease. Results: NR formation during SVG PCI was significantly higher in patients with high SII (p < 0.001). NR occurrence was 12.8% when SII was ≤548 and 41.9% when SII was >548. Conclusion: Our study is the first to investigate SII as the state of inflammation and its effect on the SVG PCI. Patients with higher SII have a higher risk of NR during an SVG for PCI.