Relationship between systemic immune-inflammation index and no-reflow in percutaneous coronary intervention for saphenous grafts

Demirci G., ŞAHİN A. A., Aktemur T., Demir A. R., Çetin İ., Karakurt H., ...More

Biomarkers in Medicine, vol.17, no.8, pp.427-435, 2023 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 17 Issue: 8
  • Publication Date: 2023
  • Doi Number: 10.2217/bmm-2023-0208
  • Journal Name: Biomarkers in Medicine
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Chemical Abstracts Core, EMBASE, MEDLINE
  • Page Numbers: pp.427-435
  • Keywords: acute coronary syndrome, no-reflow, percutaneous coronary intervention, saphenous venous graft disease, SII
  • Marmara University Affiliated: Yes

Abstract

Objective: In this study, we investigated the occurrence of no-reflow (NR) in percutaneous coronary intervention (PCI) for saphenous vein grafts (SVGs) and its relationship with a new systemic immune-inflammation index (SII) that determines inflammation. Methods: We studied 303 patients with acute coronary syndrome without ST elevation who underwent PCI for SVG disease. Results: NR formation during SVG PCI was significantly higher in patients with high SII (p < 0.001). NR occurrence was 12.8% when SII was ≤548 and 41.9% when SII was >548. Conclusion: Our study is the first to investigate SII as the state of inflammation and its effect on the SVG PCI. Patients with higher SII have a higher risk of NR during an SVG for PCI.